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Together, these results suggest that the reduction in HGP observed in HFHC-fed Dpp4 –/– mice is driven by the loss of Dpp4 in hepatocytes and not Tie2 + EC populations
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However, 16 patients dosed with 5-day cycles of LD IL-2 every two weeks (q2wks) or placebo for the same 21-week duration did not exhibit benefits in exploratory endpoints
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